If you're worried about your cholesterol, you should know that there are different types of cholesterol medicines to choose from. There are the PCSK9 inhibitors and the statins, as well as other drugs like the ezetimibe and the fibrates.
PCSK9 inhibitors
PCSK9 inhibitors are cholesterol medicines that lower LDL cholesterol levels. These drugs are usually prescribed to patients with high cholesterol and a history of heart disease. However, they can also be used in people who can't tolerate statins.
PCSK9 inhibitors are given as an injection every two to four weeks. They work by targeting and inactivating receptors on the surface of liver cells that are important for the metabolism of LDL.
When combined with other treatment methods, these cholesterol medicines can dramatically reduce LDL cholesterol. This results in less plaque buildup in blood vessels and reduced risks of heart attack and stroke.
While there are some side effects from these cholesterol medicines, they're relatively common. Most people tolerate them well. If you're interested in PCSK9 inhibitors, discuss them with your doctor. He or she will need to monitor you for a period of time to determine whether the medications are effective.
Statins
Statins are medicines that are used to help prevent heart attacks, strokes and other cardiovascular problems. They do this by lowering cholesterol levels and raising HDL ("good") cholesterol. But while they may reduce the risk of a heart attack, they also have a few downsides.
First, they are not for everybody. A few individuals have liver problems or other medical conditions that make them a poor candidate for statins. If you are one of these people, ask your doctor or pharmacist about alternative drugs.
Second, you must remember that statins are meant to be cholesterol kam karny ka Unani ilaaj. Once they are started, they should be taken for the rest of your life.
Ezetimibe
Ezetimibe is a prescription medicine used for lowering cholesterol levels in the blood. It can be taken alone or with other medications. The dosage is usually 10 mg of ezetimibe once a day.
Ezetimibe should be taken with a low-cholesterol diet. While this drug has fewer side effects than statins, there are still some risks associated with taking it. A doctor may recommend blood tests to check liver function and blood clotting.
This drug can cause serious allergic reactions in people. Call your doctor immediately if you have any signs of a severe reaction. Your doctor may prescribe you hospital treatment.
If you miss a dose, you should take it as soon as you remember. You can also set an alarm to remind you of your next dose.
Fibrates
Fibrates are a class of medicine used for lipid reduction. They are commonly prescribed for patients with hypertriglyceridemia. But they are also used for a variety of other metabolic disorders.
Besides being effective in reducing cholesterol levels, fibrates have been found to reduce the risk of heart attacks and pancreatitis. There are two types of fibrates: gemfibrozil (Lopid) and fenofibrate (Fenoglide).
Fibrates lower LDL cholesterol and triglycerides by activating a peroxisome proliferator-activated receptor alpha, a nuclear transcription factor. The PPAR-a increases lipoprotein lipase activity, resulting in more lipolysis and less VLDL. Using fibrates with statins may help to improve the effects of both.
Although statins are better able to control triglyceride and HDL levels, fibrates are often prescribed as a second-line therapy for patients who cannot tolerate statins. Some doctors prescribe them with close monitoring of their side effects.
Over-the-counter niacin
Niacin is used for a variety of lipid disorders. It works by blocking the production of blood fats, especially cholesterol and triglycerides. In addition, it can also raise the "good" HDL cholesterol and reduce the "bad" LDL cholesterol.
Niacin is available as an over-the-counter (OTC) supplement and as a prescription medication. The main difference is that an over-the-counter product is not regulated by the FDA.
Niacin is a type of B vitamin. It is found naturally in foods. Some grains, vegetables, fruits, and animal foods are sources of niacin. You can find niacin in multivitamins, but you can also buy it in niacin-only supplements.
The recommended dose of niacin for cholesterol support depends on the person. For adults, the amount should range from 500 to 1,000 milligrams per day. If your body does not absorb the nutrients properly, you may need to take a higher dosage.
Repatha and Praluent
The new cholesterol medicines Repatha and Praluent are prescribed to lower the levels of LDL (low-density lipoprotein) in the bloodstream. This helps reduce the risk of cardiovascular diseases and stroke.
These drugs are called PCSK9 inhibitors. They lower LDL cholesterol by preventing the enzyme PCSK9 from attaching to LDL receptors in the liver.
Both Repatha and Praluent are used in combination with other lipid-lowering therapies to treat patients who have heart disease. But these drugs are expensive. And high copays can prevent patients from filling their prescriptions.
Those who have genetic conditions that cause tablets for high cholesterol, or HeFH, can take Praluent to reduce their cholesterol. It can also be given to children 10 years or older to treat high cholesterol.
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