Medicine for Cholesterol

When lifestyle changes aren't enough to keep your cholesterol levels in a healthy range, medicine can help. When taken properly, medication can reduce your cholesterol and lower your risk for serious health problems, such as heart attack and stroke.

Your doctor will recommend a medication or combination of medications based on your cholesterol levels and other factors. The most common cholesterol-lowering drugs are statins. These lower LDL (“bad”) cholesterol and lower triglyceride levels.

Statins

Statins (HMG-CoA reductase inhibitors) are used to lower your cholesterol and prevent heart disease. They do this by blocking an enzyme that your body needs to make LDL cholesterol, a type of fat that can build up in your arteries and cause heart problems.

Doctors can now prescribe statins to most people who are at high risk of developing heart disease. They take many things into account when assessing this risk, including your family history of heart disease.

These drugs also help protect against heart attacks and strokes, by reducing the build-up of plaque in your blood vessel walls. They're safe when used correctly and under a doctor's supervision, so it's a good idea to consult with your doctor about which medication might be right for you.

Cholesterol absorption inhibitors

High cholesterol in the blood can lead to heart disease, which is why doctors prescribe medicines for people with elevated cholesterol levels. These medicines include statins, bile acid sequestrants (like cholestyramine and colesevelam), and cholesterol absorption inhibitors like ezetimibe.

Cholesterol absorption inhibitors are a class of medicine that reduce the amount of LDL cholesterol in your body, and may also increase HDL "good" cholesterol and lower triglycerides. They can be used alone or in combination with statins to help lower your cholesterol and protect you from heart disease.

The first ezetimibe is a new type of lipid-lowering drug that selectively inhibits cholesterol absorption in the high cholesterol ka desi ilaj. Ezetimibe works at the brush border of your small intestine to decrease dietary and biliary cholesterol from being absorbed into your bloodstream. The decreased delivery of intestinal cholesterol to your liver increases hepatic LDL receptor activity, which increases the ability of your liver to remove the cholesterol in your bloodstream and reduces your risk for heart attack or stroke.

Fibrates

One of the most common medicines your doctor prescribes is a lipid-lowering drug. This can help lower your cholesterol and other risk factors that may lead to heart disease or other health problems.

A group of medications called fibrates are used to treat high cholesterol. They work by lowering your blood triglyceride levels and raising your high-density lipoprotein (HDL) cholesterol, also called "good cholesterol."

Fibrates are usually prescribed to people who are at very high risk for cardiovascular disease (CVD). They are often given with statins, another type of medication for reducing your cholesterol and other risk factors.

They lower triglyceride levels and increase your HDL cholesterol by activating a receptor on the cell surface of your liver called peroxisome proliferator-activated receptor a (PPARa). This receptor is important in regulating fatty acid metabolism, including the synthesis and breakdown of triglycerides.

PCSK9 inhibitors

If your cholesterol levels are high, you may be able to take medicine called PCSK9 inhibitors. They work by directly modifying a gene that affects the amount of LDL cholesterol in your body.

Every person has a gene that directly controls how many of the proteins in your liver, called low-density lipoprotein receptors (LDL receptors), can sweep away excess cholesterol from the blood. Some people have mutations in this gene that lower the number of LDL receptors.

Symptoms of this genetic condition are usually mild and can be treated with statins, but even the highest dose of these drugs won’t bring cholesterol levels down to a healthy level for most people with this condition.

A new class of drugs called jigar ki charbi ka ilaj in urdu has been shown to lower cholesterol levels in animal studies and has been shown to reduce the risk of heart attacks and strokes in people with high cholesterol or a genetic condition that causes very high cholesterol. They are used together with statins or as a stand-alone treatment for people who can’t tolerate statins or who have a genetic condition that increases their risk of high cholesterol.